Acute hemorrhagic edema of infancy

Notes

## Basic introduction

  • Acute hemorrhagic edema of infancy (AHEI) is a leukocytoclastic vasculitis of infants
  • It affects children between 4 months and 2 years of age
  • It is thought to be an immune complex disorder whose triggers include the following:
  • URTIs
  • Cytomegalovirus
  • Medications
  • Pneumonia
  • Pulmonary TB
  • Staphylococcal infections
  • Streptococcal infections
  • UTIs
  • Viral infections

## Statistics

  • It is a generally uncommon illness
Symptoms
  • Purpura
  • Oedema
  • Fever
Diagnosis
  • Clinical review
Differential
  • Acute Febrile Neutrophilic
  • Acute Urticaria
  • Child Abuse
  • Dermatosis
  • Drug Eruptions
  • Erythema Multiforme
  • Hypersensitivity Vasculitis
  • Purpura
Prevention
  • No known method exists for prevention of AHEI
Reference

1. Crowe, M. A., & Jonas, P. P. (1998). Acute hemorrhagic edema of infancy. Cutis, 62(2), 65-66.

Management
  • It does not require any treatment
  • It resolves spontaneously over 1-3 wks with complete recovery
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