Trichuriasis

Notes
  • It is caused by Trichuris trichiura or whipworms
  • Statistics: size of the worms-30 to 50mm; life span - 1 to 2yrs; time to maturity - 1 to 2 months; 3rd most prevalent round worm; People affected by the worm globally- 800 millions; single-celled eggs per day - 2,000 to 10,000
  1. Transmission
  • Life cycle;

_Eggs are deposited to soil

_Eggs become embryonated and enter the “infective” stage (after 2-3 wks)

_Eggs ingested by human

_Eggs hatch in the human small intestine

_The infective larvae penetrate the villi

_The larvae develop in the small intestine into young worms

_The young worms move to the caecum and ascending colon, penetrate the mucosa, mature, mate and lay eggs.

Symptoms
  • Mainly asymptomatic
  • Abdominal pain
  • Loss appetite
  • Diarrhea
  • Anemia
  • Retarded growth
  • Weight loss
  • Rectal prolapse (mainly in children)
Diagnosis
  • Stool microscopy for ova
Management

Either,

Over 2 years: (children and adults): _Tabs/susp Albendazole 400mg stat

Or;

_Tabs Levamizole Adults: 120mg stat. Children 1-4 years: 40mg stat.  5-15 years: 80mg stat.

Or;

_Tabs Mebendazole 100mg BD x 3/7 or 500mg stat.

Or;

Tabs / susp Pyrantel pamoate 10mg/kg stat

Or;

Rarely:

   _ Ivermectin 200 mcg/kg OD x 3/7

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