Poisoning – Zinc Phosphide

Notes
  • Zinc phosphide is the active ingredient of some rodenticides whose poisoning is mainly suicidal attempts.
  • Once it is ingested it is converted into phosphine gas.
  • The mortality rate of its poisoning is 37-100%
  • As a result of the extensive damage to the heart and the lungs, the patients die early in treatment.
Symptoms
  • Nausea
  • Vomiting
  • Diarrhea
  • Retrosternal pain
  • Shortness of breath,
  • Cyanosis
  • Circulatory collapse
  • Hypotension
  • Shock symptoms
  • Myocarditis
  • Pericarditis
  • Acute pulmonary edema
  • Congestive heart failure
  • Hepatomegaly
  • Liver failure
  • Severe hypoglycaemia
  • Delirium
  • Tonic-clonic seizures
  • Acute severe metabolic acidosis
Diagnosis
  • Clinical
Management
  • It has no specifc antidote
  • IV fluids in severe case
  • Activated charcoal
  • Intubation and mechanical ventilation in severe cases
  • Dopamine
  • Infusion to correct hypotension
  • Monitor the functions of vital organs and metabolic parameters.
Drug Index 2.0 is here
Our new update features a more powerful search feature and easier login. Having any issues? Contact us today. Contact Us