*Fasciculins that destroy acetylcholinesterase causing tetany and death. They are found in mambas & rattlesnakes.
*Dendrotoxins that block the exchange of positive and negative ions across the neuronal membrane causing paralyzing and death. They are found in mambas.
*α-neurotoxins that fit to the Nicotinic acetylcholine receptors of cholinergic neurons causing paralyzing and death. They are found mainly in cobra and sea snakes.
*Phospholipases that act on phospholipid molecule of the cell membrane leading to their rapture. Snake venoms also contain other hydrolytic enzymes that include proteinases and nucleotidases.
Mangement in hospital
*Inoserp Antivenom®, Inosan, inj., polyvalent antivenom against snakebite envenomation [10ml= Kes: 10,727.25]
Anti-snakevenom, Serum Institute, 10ml amp [10ml amp = Ke:3548.00].
*Snake venom Antiserum [African], Vins, equine immunoglobulin fragments [10ml vial = Ke:7,228.00].
Dose: At least one vial is infused.