Hepatitis Virus C infection

Notes
  • Causes acute and chronic infection
  • Parenteral spread
  • Infection increases risk of hepatocellular carcinoma
Symptoms
  • Acute hepatitis;

_Fever

_Malaise

_Jaundice, itchness dark urine and light stool due to increased plasma levels of bilirubin.

_Elevated levels of ALT and AST in LFTs

_Elevated WBCs levels

Diagnosis
  • History: risky sexual activity and possibility of being being IV Drug User should be considered.
  • Anti-HCV IgM test (for current or recent infection)
  • Anti-HCV IgG test (for chronic illness)
  • Molecular diagnostic (PCR)
Management
  • Supportive treatment
  • HBC immunoglobulins
  • Peglated interferon alpha 2b
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