## Basic introduction
_Autoimmune destruction of melanocytes
_Functional defects of melanocytes
## Risk factors
It is classified as:
1. Ezzedine, K; Eleftheriadou, V; Whitton, M; van Geel, N (4 July 2015). "Vitiligo.". Lancet (London, England). 386 (9988): 74–84.
2. Whitton, ME; Ashcroft, DM; González, U (Oct 2008). "Therapeutic interventions for vitiligo.". Journal of the American Academy of Dermatology. 59 (4): 713–7.
_Vitiligo on the neck and face that have been in existence for < 3yrs takes few weeks to treat
_Vitiligo on the hands and legs that have been in existence for >3yrs takes months to treat
_Psoralens are meant to increase the skin's sensitivity to UV in order to improve the treatment outcome but care should be taken as it can cause sunburn-type reactions and skin freckling when administered excessively.
_NBUVB treatment is an alternative to PUVA that has the benefit of causing less side-effects while it is as effective as PUVA