♦This is the most common form of EC.
♦It is an estrogen-dependent neoplasm that begins as proliferation of normal tissues to hyperplasia and then eventually to cancer.
♦It is unrelated to estrogen and hyperplasia.
♦It is a more aggressive tumor than Type 1
_Endometroid (which is a ciliated adenocarcinoma with a prevalence of 75 – 80%).
_Papillary (which has poor prognosis, acts like ovarian cancer and it is manifested in stage IV of EC)
_Metrorrhagia (bleeding between menstrual cycle).
_Menorrhagia (heavy menstrual bleeding)
_Watery blood-tinted discharge in between menstrual periods.
_Bleeding after menopause
_Total abdominal hysterectomy (TAH)
_Pelvic and para-aortic lymphadenectomy
_Peritoneal washings for cytology
_Radiation therapy (internal and external) for Stage 1-II
_For Stage III-IV: external radiation; hormonal therapy (mainly progestin therapy).
_Chemotherapy: doxorubicin, cisplatin, carboplatin and paclitaxel