ENT, UTI, RTI, skin and soft tissues, bone, joint, GI, intra-abdominal, pelvic and severe infections, gonorrhoea.
Orally, Respiratory-tract infections, 500– 750mg twice daily (750mg twice daily in pseu- domonal lower respiratory-tract infection in cystic fibrosis). Urinary-tract infections, 250– 750mg twice daily (250mg twice daily for 3 days usually adequate for acute uncomplicated cystitis in women). Acute or chronic prostatitis, 500mg twice daily for 28 days. Gonorrhoea, 500mg as a single dose. Surgical prophylaxis, 750mg 60 minutes before procedure. Prophylaxis of me
ningococcal meningitis, I.V infusion over 60 minutes, 400mg every 8–12 hours. Anthrax (treatment and post-exposure prophylaxis), oral- ly, 500mg twice daily, I.V infusion over 60 minutes, 400mg every 12 hours. Complicated urinary-tract infections, orally, Neonate 7.5 mg/kg twice daily, Child 1 month–1 year 5– 7.5 mg/kg twice daily; dose doubled in severe in- fection, 1–18 years 10mg/kg twice daily; dose doubled in severe infection (max. 750 mg twice daily), I.V infusion over 60 minutes, Neonate 5mg/kg every 12 hours, Child 1 month–1 year 4mg/kg every 12 hours; dose doubled in severe infection, Child 1–18 years 6mg/kg every 8 hours; increased to 10 mg/kg every 8 hours in se- vere infection (max. 400 mg every 8 hours). Se- vere respiratory-tract infections, gastro- intestinal infections: Orally
Neonate 7.5 mg/kg twice daily, Child 1 month–1 year5–7.5mg/kgtwicedaily;dosedoubledin severe infection, Child 1–18 years 20 mg/kg (max. 750 mg) twice daily, I.V infusion over 60 minutes
Neonate 5 mg/kg every 12 hours, Child 1 month– 1 year 4 mg/kg every 12 hours; dose doubled in severe infection, Child 1–18 years 10 mg/kg (max. 400 mg) every 8 hours. Pseudomonal low- er respiratory-tract infection in cystic fibrosis, orally, 1 month–1 year 15 mg/kg twice daily, 1– 18 years 20mg/kg (max. 750mg) twice dail, I.V over 60 minutes, 1 month–1 year 4–8mg/kg every 12 hours, 1–18 years 10mg/kg (max. 400mg) eve- ry 8 hours. Gonorrhoea, orally, 12–18 ye