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It acts as a coenzyme for various metabolic functions such as protein synthesis and fat and carbohydrate metabolism.
Hypokalaemia and sudden death may occur in severe megaloblastic anaemia that is treated intensively with vitamin B12.
Early signs of Leber's disease; hypersensitivity to Vitamin B12.
Hypersensitivity reactions; diarrhoea; formation of antibodies to the hydroxoco- balamin-transcobalamin II complex.
||| Cyanocobalamin and hydroxocobalamin are synthetic forms of Vitamin B12. Cyanocobalamin and hydroxocobalamin have similar indications but hydroxocobalamin may be preferred for treatment of B12 deficiency since optic neuropathies may degenerate with administration of cyanocobalamin.