Moderate to severe active rheuma- toid arthritis; Crohn's disease; ankylosing spondy- litis; ulcerative colitis; plaque psoriasis; psoriatic arthritis.
5mg/kg at 0, 2 and 6 wks then every 8 weeks thereafter
Mode of action
Brands containing this Ingredient
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Mode of Action
A chimeric monoclonal antibody that binds to TNFα, neutralizing it and preventing its binding to its receptors.
Active infection; treated HBV infec-
Moderate to severe HF
Infusion-related reactions such as dyspnea, flushing, headache and rash; delayed hypersensitivity reactions such as serum sickness; combination of arthralgia and/or myalgia with fever and/or rash; increased frequency of infec- tions such as RTIs and UTIs; malignancies such as non-Hodgkin's lymphoma and Hodgkin's disease; fatigue.