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Gentamicin
Indications
Sensitive UTI, RTI, severe systemic infections, bone and tissue infections, eye infections.
Dose/Application
Adult: Multiple daily dose regimen, by intramuscular or by slow intravenous injection over at least 3 minutes or by intravenous infu- sion, 3–5 mg/kg daily [in divided doses every 8 hours.Endocarditis [in combination with other antibacterials, adult 1 mg/kg every 8 hours Once daily dose regimen, by intravenous infu- sion, initially 5–7 mg/kg, then adjust according to serum-gentamicin concentration By intrathecal injection, seek specialist advice, 1 mg daily [increased if necessary to 5 mg daily] Child: Neonatal sepsis, extended interval dose regimen by slow intravenous injection or intrave- nous infusion. Neonate less than 32 weeks post- menstrual age 4–5 mg/kg every 36 hours Neonate 32 weeks and over postmenstrual age 4– 5mg/kg every 24 hours. Multiple daily dose regimen by slow intravenous injection. Neonate less than 29 weeks postmenstrual age 2.5 mg/kg every 24 hours. Neonate 29-35 weeks postmen- strual age: 2.5 mg/kg every 18 hours. Neonate over 35 weeks postmenstrual age: 2.5 mg/kg every 12 hours Septicaemia, meningitis and other CNS infecendocarditis, pneumonia in hospital patients, adjunct in listerial meningitis Once daily dose regimen [not for endocarditis or meningitis] by intravenous infusion. Child 1 month-18 years initially 7 mg/kg, then adjusted according to serum-gentamicin concentration Multiple daily dose regimen by intramuscular or by slow intravenous injection over at least 3 minutes. Child 1 month-12 years 2.5 mg/kg every 8 hours. Child 12-18 years 2 mg/kg every 8 hours Pseudomonal lung infection in cystic fibrosis By slow intravenous injection over at least 3 minutes or by intravenous infusion. Child 1 month-18 years 3 mg/kg every 8 hours. Bacterial ventriculitis and CNS infection [supplement to systemic therapy]. By intrathecal or intraventric- ular injection, seek specialist advice Neonate seek specialist advice. Child 1 month–18 years: 1 mg daily [increased if necessary to 5 mg daily]
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Mycin Inj 80mg/mL 10 KES120.00
Gentamed_injection inj 80mg/2ml 1 KES3.65
Dawagenta inj 80mg/2ml 1 KES80.00
Genacyn. inj 20mg/2mL 25 KES300.00
Genacyn. inj 80mg/2ml 25 KES494.00
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