HIV (in combination with other ARVs). It is infrequently used as a sole PI due to its poor absorption profile.
600mg TID. Taken with food.
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Brands containing this Ingredient
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Monitoring of aminotransferases, cholesterol, and triglycerides preferably on a bi-monthly basis; it is metabolized in the liver hence its dose reduced in serious hepatic impairment.
Predisposition to cardiac arrhythmias (including congenital QT prolongation, bradycardia, history of symptomatic arrhythmias, heart failure with reduced left ventricular ejection fraction, electrolyte disturbances, concomitant use of drugs that prolong QT or PR interval); concomitant use of drugs that increase plasma-saquinavir concentration (avoid unless no alternative treatment available), efavirenz; rifampicin and amiodarone.
Abdominal pain; flatulence; dry eyes; cough; oral ulcers and general weakness.