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Benzylpenicillin
Indications
Streptococcal (including pneumococcal), gonococcal, and meningococcal infections, anthrax, diphtheria, gas-gangrene, leptospirosis, lyme disease.
Dose/Application
For most infections, doses of 0.6 to 4.8 g of benzylpenicillin daily in 2 to 4 divided doses by intramuscular or slow intravenous injection or intravenous infusion may be adequate, but higher doses given intravenously, often by infusion, are more usual for severe infections. Mild to moderate susceptible infections [including throat infec- tions, otitis media, pneumonia, cellulitis, neonatal sepsis]. By intramuscular injection or by slow intravenous injection or infusion [intravenous route recommended in neonates and infants] Neonate under 7 days: 25 mg/kg every 12 hours; dose doubled in severe infection. Neonate 7–28 days: 25 mg/kg every 8 hours; dose doubled in severe infection Child 1 month–18 years: 25 mg/kg every 6 hours; increased to 50 mg/kg every 4–6 hours [max. 2.4 g every 4 hours] in severe infection Endocarditis [combined with another antibacte- rial if necessary] By slow intravenous injection or infusion Child 1 month–18 years: 25 mg/kg every 4 hours, increased if necessary to 50 mg/kg [max. 2.4 g] every 4 hours Meningitis, meningococcal disease By slow intravenous injection or infusion Neonate: 75 mg/kg every 8 hours Child 1 month–18 years: 50 mg/kg every 4–6 hours [max. 2.4 g every 4 hours] Proven or suspected neonatal group B strepto- coccus infection By slow intravenous injection or infusion Neonate under 7 days: 50 mg/kg every 12 hours Neonate 7–28 days: 50 mg/kg every 8 hours
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Medipen inj 1 Mega units 1 KES6.00
Medipen inj 5 Mega units 1 KES24.00
Benzyl penicillin, by Dawa inj 1 Mega units 1 KES12.00
Benzyl penicillin, by Dawa inj 5 Mega units 1 KES30.00
Benzyl penicillin G inj 1 mega unit 1 KES10.00
Benzyl penicillin G inj 5 Mega unit 1 KES30.00
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