0.25mg/kg, increasing to 1mg/kg by slow infusion in 5% glucose.
Mode of action
Brands containing this Ingredient
Amphotericin, by Medisel
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Mode of Action
The drug probably acts by binding to the ergosterol in the fungal cell membrane causing mem-brane damage and subsequent leakage of cell contents. It has a higher affinity for ergosterol in the fungal cell membrane than in human.
Monitoring of renal function
Avoid in patients known to be allergic to any of its constituents.