Symptomatic treatment of chronic stable angina pectoris; chronic heart failure
2.5-5mg BD [max. dose 7.5mg BD]
Mode of action
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Mode of Action
Heart rate lowering agent, acting by selective and specific inhibition of the cardiac pace- maker If current that controls the spontaneous diastol- ic depolarization in the sinus node and regulates heart rate.
Allergy to the drug and excipi- ents; resting heart rate below 70 beats per minute prior to treatment; cardiogenic shock; acute myocardial infarction; severe hypotension; severe hepatic insufficiency; sick sinus syndrome; unstable or acute heart failure.