Simple Vitamin D deficiency due to nutritional; hypophosphataemia.
For Vit. D deficiency: 400 I.U of Vit. D. For Vit. D deficiency caused by intestinal malabsorption or chronic liver disease; 40,000 I.U daily of calciferol. For hypocalcemia of hypopar- athyroidism: Up to 100,000 I.U daily.
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Vitamin D3[cholecalciferol] and Vitamin D2[ergocalciferol] - which are natural forms of Vitamin D]- are transported to the liver where they are converted to calcifediol [25- hydroxycholecalciferol]. This is then transported to the kidneys and converted to calcitriol [1, 25- dihydroxycholecalciferol], which is thought to be the most active form of Vitamin D. It is required for absorption of calcium and phosphorus from the intestine. It also controls the amount of calcium in the bones [with parahormone]. These active forms of vitamin D should be prescribed in severe renal impairment when there is require- ment of Vitamin. D therapy.
Bone pain; constipation; diarrhea; drowsiness; dry mouth; headache; metallic taste; muscle pain; nausea; vomiting; increase in frequency of urination [especially at night] or in the amount of urine; loss of appetite; unusual tiredness or weakness; cloudy urine; lethargy; loss of appetite; pancreatitis; psychosis; conjunctivitis; decreased libido; ectopic calcification; high fever; hypertension; increased sensitivity of eyes to light or irritation of eyes; irregular heartbeat; itching of skin; rhinorrhea; and weight loss.