Prophylaxis and treatment Vitamin B12deficiency; treatment of pernicious anemia
Depends on the degree of deficiency. Otherwise, 100 mcg daily for 6 or 7 days should be given by IM or deep SC then on alternate days for seven doses followed by every 3 to 4 days for another 2 to 3 weeks.
Mode of action
Brands containing this Ingredient
Cyanocobalamine, by Medisel
Cyanocobalamine, by Metro
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Mode of Action
It acts as a coenzyme for various metabolic functions such as protein synthesis and fat and carbohydrate metabolism.
Hypokalaemia and sudden death may occur in severe megaloblastic anemia that is treated intensively with vitamin B12.
Early signs of Leber's dis-ease; hypersensitivity to Vitamin B12.
Hypersensitivity reactions; diarrhea; formation of antibodies to the hydroxocobalamin-transcobalamin II complex.
Cyanocobalamin and hydroxocobalamin are synthetic forms of Vitamin B12. Cyanocobalamin and hydroxocobalamin have similar indications but hydroxocobalamin may be preferred for treatment of B12 deficiency since optic neuropathies may degenerate with the administration of cyanocobalamin.