Organic and idiopathic venous diseases such as chronic venous insufficiency [CVI] of the lower limbs with symptoms that include heavy legs; pain; nocturnal cramps; haemorrhoidal disease.
In venous insufficiency: 1 tablet daily half-hour before the morning meal. In hemorrhoids: 2 to 3 tablets daily with meals
Mode of action
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Mode of Action
Vascular protector and venotonic that acts on the return vascular system reducing venous distensibility and venous stasis. It also normalizes capillary permeability besides reinforcing capillary resistance.
It is generally well-tolerated, including in pregnancy, with a lower or identical rate of side effects as placebo. Mild GI symptoms such as nausea and gastric discomfort or mild autonomic symptoms such as headache and vertigo
Safety in pregnancy and lactation: It can be used in the 2nd and 3rd trimester and during lactation.