25mg OD and must be taken with meals. The dose is doubled to 50mg OD if the patient is concomitantly receiving rifabutin. Repeat the dose if a patient vomits within 4 hrs of taking the medicine
Mode of action
Brands containing this Ingredient
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Mode of Action
Non-competitive inhibition of HIV-1 reverse transcriptase (RT).
Allergy to any component of the formulation, and drugs that induce CYP3A enzymes such as rifampicin, dexamethasone, carbamazepine, oxcarbazepine, phenobarbital and phenytoin, and proton pump inhibitors.
Loss of appetite, insomnia, and vomiting sometimes somnolence, headache, dizziness, dry mouth, abdominal discomfort, fatigue, and allergic reaction.