Local anesthesia [in adults and children above 12 yrs]. See under the "Dosage" below for details.
Adjustment of the dose should be dictated by the response of the patient. The dose is based on lignocaine. Surgical procedures where infiltration is required: up to 150mg of lignocaine (or 15mL of 1% solution). Postoperative pain, fractured ribs and surgical procedure where Intercostals block is required: up to 150mg (normal range 20-50mg (2-5mL max. 15mL of 1% solution). Instrumental delivery: Pudendal field block with 100mg (or 10mL of 1% solution). To inject slowly (at a rate of 100-200 mg/min).
Mode of action
Brands containing this Ingredient
Locaine A dental Cartridges.
20mg (2%)/12.5ug (1:80,000): 1.8mL.
20mg (2%)/12.5ug (1:80,000):1.8mL.
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Mode of Action
Lignocaine acts by stabilizing the membranes of the nerve cells by decreasing their permeability to sodium ions. Adrenaline, a vasoconstrictor, prevents the extensive spread of lignocaine.
Avoid IV administration. Epilepsy, elderly patients, cardiac disorders.
Children below 12yrs. Allergy to any component of the formulation. Use on fingers, toes, the tip of nose, ears, and penis since the product contains adrenaline.
Acute toxic reactions in case of accidental intravascular injection. Drowsiness; dizziness; disorientation; confusion; lightheadedness; psychosis; apprehension; tinnitus; visual disturbances including amblyopia or diplopia; nausea; vomiting; paraesthesia; sensations of heat, cold, or numbness; difficulty swallowing; dyspnea; and slurred speech; muscle twitching or tremors, seizures, unconsciousness, coma, and respiratory depression; hypersensitivity reaction; hypotension, arrhythmias, heart block; local thrombophlebitis.