Postpartum uterine haemorrhage; medical induction of labour; augmentation of labour; hypotonic uterine inertia; diagnosis of utero-placental insufficiency [oxytocin challenge test]; treatment of lactation deficiency [mostly intranasally]; diagnosis of foetal distress
Single IV bolus inj, 100mcg
Mode of action
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Mode of Action
It acts by increasing intracellular calcium concentrations in the uterine myometrium, which contains receptors specific to oxytocin, thus inducing contractions. It induces lactation by stimulating the smooth muscle to help the discharge of milk from breasts
Hypertension; cardiac disease; renal function impairment
Fibrinogenaemia; pelvic hematoma; postpartum hemorrhage: allergic reactions; cardiac arrhythmias; hypotension followed by hypertension; uterine rupture; water intoxication; nausea; vomiting.