Oedema: 5-10mg OD or on alternate days, maintenance: 2.5-10mg 1-3 times weekly. Hypertension: 2.5mg OD (Higher doses may not be required).
Mode of action
Brands containing this Ingredient
Bendroflumethiazide, by Metro
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Mode of Action
Inhibits reabsorption of sodium and chloride ions in the cortical thick ascending limb of the loop of henlē and early distal tubules. It has direct antihypertensive effect requiring several days to be manifested.
May aggravate diabetes, gout & systematic lupus erythematous. May cause hypokaleamia. Pregnancy and lactation, elderly, renal/hepatic impairment, withdraw several days before commencing ACE inhibitor treatment.
Anuria, renal decompensation, hypersensitivity to thiazide and related diuretics or sulphonamides, hepatic coma, hyponatreamia, refractory hypokaleamia, hyperuricaemia, addisonâs disease.
GI disturbances, hypokalaemia, manifestations of latent diabetes, sensitivity reactions, blood dyscrasias, postural hypotension, reversible impotence, gout, pancreatitis, blurred vision, muscle spasm, hypomagnesia, natraemia and chloraemic alkalosis, and hypercalceamia.