Drying of bronchial and salivary secretions due to inhalations in anesthetics and intubations; prevention of the onset of bradycardia and other muscarinic action due to neostigmine; diagnosis of sinus node dysfunction and in the evaluation of coronary artery disease during atrial pacing; Organophosphorous poisoning as an antidote.
Premedication: By I.V inj. 300-600mcg immediately before anesthesia. Dose increased by 100mcg for the treatment of bradycardia. Organophosphorus poisoning: I.M or I.V 2mg every 20-30mins until the skin becomes dry, the pupils dilate and tachycardia develops.
Mode of action
Brands containing this Ingredient
Atropine sulphate, by Medisel
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Prostate enlargement, paralytic ileus, pyloric stenosis, high ambient temperatures.
Dry mouth; blurred vision; cyclo-plegia; mydriasis; photophobia anhidrosis; urinary hesitancy and retention; tachycardia; increased ocular tension; loss of taste sensation; headache; nervousness; drowsiness; weakness; dizziness; flushing, insomnia; nausea and vomiting; bloated feeling; mental confusion and/or excitement [especially in geriatric patients].
General notes: It is a classical antimuscarinic that is usually obtained by extraction from various members of the Solanaceae genus of plants including Atropa, Datura stramonium, or Duboisia myoporoides.