Squamous cell carcinoma; lymphomas; testicular carcinoma; malignant pleural effusions [where it is used as a sclerosing agent].
Due to the risk of an idiosyncratic reaction in lymphoma patients, one test dose of 1 - 2 Units or less is given 2-4hrs before the initiation of therapy at regular dosage.Consult specialist literature for further information.
Mode of action
Brands containing this Ingredient
Drug Index 2.0 is hereOur new update features a more powerful search feature and easier login.
issues? Contact us
today. Contact Us
Mode of Action
It is thought to inhibit DNA synthesis and to a lesser extent inhibits RNA and protein synthesis.
Administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents; impairment of renal function; impairment of pulmonary function; to advise to avoid pregnancy during therapy with bleomycin.
Hypersensitive or an idiosyncratic reaction to bleomycin
Progressive pulmonary fibrosis [most common and serious S/E]; dermatological toxicity; renal toxicity; hepatic toxicity; mucositis; hypersensitivity or idiosyncratic reactions
This is a cytotoxic agent that causes little bone marrow suppression. It is a mixture of glycopeptide antibiotics isolated from a strain of Streptomyces verticillus. It is used either as a single agent or in proven combinations with other approved chemotherapeutic agents.