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Chronic myelogenous leukemia [CML]; myeloproliferative disorders like severe thrombocytosis and polycythemia vera; an adjunct in the treatment of myelofibrosis; a component of pretransplant conditioning regimens in patients undergoing bone marrow transplantation for non-malignant diseases.
Usual dose in adult and children: 0.065-0.1 mg/kg daily. It is individualized based on clinical and haematologic response and tolerance of the patient. Consult specialist literature for further information.
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