Aborting pregnancy 13th-20th wks of gestation and in the 2nd trimester due to various clinical causes; postpartum haemorrhage due to uterine atony unresponsive to conventional methods of management such oxytocin.
250mcg IM and subsequent doses of 250mcg 1½- 3½ hours intervals depending on uterine response [not to exceed 12mg and continuous administration for more than 2 days]
Mode of action
Brands containing this Ingredient
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Mode of Action
Stimulates gravid uterus to produce myometrial contractions
History of asthma, hypo- or hyper-tension, cardiovascular, renal, or hepatic disease, anemia, jaundice, diabetes, or epilepsy. Compromised [scarred] uteri
Acute PID; active cardiac, pulmonary, renal or hepatic disease; hypersensitivity to the active substance or to any of the excipients
Generally transient and reversible when therapy ends as they are mostly related to its contractile effect on smooth muscle. They include:vomiting; diarrhea; nausea; flushing or hot flashes; chills or shivering; coughing, head-aches; endometritis; hiccough; dysmenorrhea-like pain; paresthesia; backache; muscular pain
15S]-15-methyl prostaglandin F2α tromethamine salt