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Imipenem / Cilastatin
Indications
Aerobic and anaerobic gram +ve and -ve bacterial infections. Septicaemia, endocarditis, gynaecological infections, mixed infections, bone, joints, skin and soft tissue infections
Dose/Application
By intravenous infusion, in terms of imipenem, 1–2 g daily [in 3–4 divided doses]; less sensitive organisms, up to 50 mg/kg daily [max. 4 g daily] in 3–4 divided doses; child 3 months and older, 60 mg/kg [up to max. of 2 g] daily in 4 divided doses; over 40 kg, adult dose Surgical prophylaxis, 1 g at induction repeated after 3 hours, supplemented in high risk [e.g. colorectal] surgery by doses of 500 mg 8 and 16 hours after induction. Children: < 1 week old; >1.5g BW: 5mg/kg IV 12hourly for non-CNS infections, 1- 4 weeks old; >1.5 g BW: 25mg/kg IV 8hourly for non-CNS infections. 4 weeks old-3 months old; >1.5 g BW: 25mg/kg IV 6hourly for non-CNS infections. >3 months old: 15-25 mg/kg/dose IV 6hourly for non-CNS infections; not to exceed 2g/day for fully susceptible organisms or 4g/day for moder- ately susceptible organisms. >12 years old: 10- 15 mg/kg IM 6hourly for mild to moderate infections Cystic fibrosis patients, up to 90 mg/kg/day IV used in older children.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Pantin inj 500mg/500mg 1 KES1,800.00
Tienam inj 500mg/500mg 1 KES2102.00
Alimpenam C Inj 500mg/500mg 1 KES1710.00
Bacqure. inj 1gm 1 KES1620.00
Imbac. inj 500mg/500mg 1 KES1971.00
Lastinem. inj. 500mg 1 KES1800.00
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