Prevention of bronchial asthma [not for acute attack] not well controlled by the bronchodilators.
Adult and children over 16yrs; 100-1000mg BD: Children over 6 years; 50-100mg BD.
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It is a corticosteroid prodrug that is enzymatically hydrolyzed to a pharmacologically active metabolite, C21-desisobutyryl-ciclesonide after oral inhalation. The exact mechanisms of corticosteroid action in asthma are not fully known.
Active pulmonary TB; airways obstruction; times of stress; gradual withdrawal of systematic steroid therapy; respiratory infections.
Status asthmaticus; safety in pregnancy and lactation not yet fully established; acute asthma attack; untreated airways infections; recurrent nasal bleeding.
Throat candidiasis; hoarseness of the voice; throat irritation; paradoxical bronchospasm [discontinue]; adrenal suppression; cataract formation after prolonged use; cutaneous hypersensitivity reactions; cough and sneeze due to irritation; pulmonary infiltrates.