Septicaemia, meningitis in neonates and infants, peri-operative infections’ prophylaxis, UTI, RTI, bone, joints, skin and soft tissue infections.
By I.M or I.V injection or infusion, 1g every 12hours increased in severe infections [e.g. meningitis] to 8g daily in 4 divided doses; higher doses [up to 12g daily in 3–4 divided doses] may be required; neonate 50mg/kg daily in 2–4 divided doses increased to 150–200 mg/kg daily in severe infections; child 100–150 mg/kg daily in 2–4 divided doses increased up to 200mg/kg daily in very severe infections.
Gonorrhoea, 500 mg as a single dose.
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