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Eptifibatide
Indications
Acute coronary syndromes (unstable angina/non ST-segment elevation myocardial infarction), including patients who are to be managed medically and those undergoing percutaneous coronary intervention.
Dose/Application
Acute Coronary Syndrome - IV bolus 180 μg/kg as soon as possible following diagno- sis, followed by a continuous infusion of 2.0 μg/kg/min until hospital discharge or initiation of CABG surgery, up to 72 hours. If a patient is to undergo a percutaneous coronary intervention [PCI] while receiving eptifibatide, the infusion should be continued up to hospital discharge, or for up to 18-24 hours after the procedure, which- ever comes first, allowing for up to 96 hours of therapy. Patients with creatinine clearance less than 50 mL/min -IV 180 μg/kg as soon as possible following diagnosis, immediately followed by a continuous infusion of 1.0 μg/kg/min. Percutane- ous Coronary Intervention [PCI] - IV 180 μg/kgadministered immediately before the initia- tion of PCI followed by a continuous infusion of 2.0 μg/kg/min and a second 180 μg/kg bolus 10 minutes after the first bolus.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
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