Prevention of chemotherapy induced neutropenia in bone marrow transplantation and severe chronic neutropenia. It generally reduces the incidence of infection.
Starting dose of 5-10 mcg /kg/day, administered as a single daily injection by SC bolus injection, by short IV infusion [15-30 minutes], or by continuous SC or IV. Consult specialist literature for further information.
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Granulocyte-colony-stimulating factor that chiefly affects the proliferation and differentiation of neutrophils within the bone marrow and other sites such as the spleen.
History of autoimmune disease
Hypersensitivity to filgrastim
Excessive leukocytosis, redness / pain at site of SC injection; allergic reactions; splenomegaly; transient supraventricular arrhythmia; vasculitis
It is a biosynthetic haematopoietic agent that chiefly affects the proliferation and differentiation of neutrophils within the bone marrow and other sites such as the spleen.