By mouth, 250–500 mg every 6 hours or 0.5–1g every 12 hours; up to 1g every 6 hours in severe infections; child, 25–50mg/kg daily in 2–4 divided doses.
By deep I.M injection or by I.V injection over 3–5 minutes or by I.V infusion, 0.5–1g every 6 hours, increased to 8g daily in severe infections; child 50–100mg/kg daily in 4 divided doses.
Surgical prophylaxis, by deep I.M injection or by I.V injection over 3–5 minutes, 1–2g at induction
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