50mg is administered initially in a single
dose at bedtime. The dose may be raised in
increments of 50 mg a day at intervals of 4-7
days. Doses above 100mg should be taken in two
divided doses. Usual adult dose: 300mg daily.
Mode of action
Brands containing this Ingredient
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Mode of Action
Acts by selectively inhibiting the re-uptaking of serotonin [less sedative than tricylics].
Renal impairment; hepatic impair- ment; withdraw gradually; diabetes; epilepsy;discontinue if seizure develop; elderly; under-
weight patients as it may lead to massive weight
loss; ECT therapy; patients with suicidal tenden-
Safety in pregnancy, lactation
and children has not been established; severe
renal failure; manic phase of depression; within
14 days of MAOI administration; avoid MAOI 5
weeks after discontinuation of fluvoxamine
[concurrent use results in confusion, agitation,
restlessness, GI symptoms, hyperpyretic episodes, severe convulsions, hypertensive crises,
the serotonin syndrome, or death]; hypersensitivity to fluvoxamine and related drugs.