Prevention of venous thromboembolism in high risk surgery
Prevention of venous thromboembolism: 2.5mg SC OD for 5-9 days. The first dose is given 6 hours after closure and when haemostasis has been established and it may be continued for up to 31 days. Treatment of venous thromboembolism: <50kg, 5mg OD; 50â100kg, 7.5mg OD; > 100kg, 10mg OD.
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Mode of Action
Selective inhibitor of activated factor X that blocks both thrombin and thrombus formation.
Active bleeding; creatinine clearance of less than 30mL/minute; acute bacte- rial endocarditis.