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Insulins
Indications
Diabetes mellitus; diabetes keto-acidosis; gestational diabetes mellitus; malnutrition-related diabetes mellitus; diagnosis of growth hormone deficiency.
Dose/Application
The starting dose should be 10-16 units of soluble insulin SC 30 minutes before meal TID. The dose is adjusted gradually in 5 unit aliquots to achieve plasma glucose range of 8.3-13.4 mmol/L in hospital and target the range of 4-10mmol/L at home. Once the blood glucose stabilizes at 8-11.0 mmol/L the patient is switched to the intermediate insulin whose dose is 2/3 of the total dose of soluble insulin. Normally 2/3 of the intermediate insulin is administered in the morning and 1/3 before supper. Management of Diabetes Ketoacidosis (DKA): Initial fluid replacement with normal saline then 5% dextrose until blood glucose is 12-14.5mmol/L then revert to normal saline until ketonuria is not detectable and fluid loss is rectified. Ten (10) units IV then 10 units IM immediately followed by 6-10 units every hour until the blood sugar of 14mmol/L is reached. This is followed by soluble insulin 8-16 units SC 4-6 hourly then TID and subsequently intermediate insulin as previously described.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Biosulin R Injection (Regular Human Insulin) inj 100IU/mL:10mL 1 KES555.00
Mixtard 30, Human Insulin inj Soluble 30%/NPH 70%, 100iu/mL:10mL 1 KES506.00
Actrapid, Human Insulin. inj soluble or regular Insulin, 100iu/mL:10mL 1 KES506.00
Insulatard, Human Insulin. inj NPH, 100ui/mL:10mL 1 KES506.00
Insulatard, Human Insulin. Penfill NPH,100IU/mL:3mL 5 KES3748.00
Mixtard 30, Human Insulin Penfill Soluble 30%/NPH 70%, 100iu/mL:3mL 5 KES3748.00
Actrapid, Human Insulin. Penfill soluble or regular Insulin, 100iu/mL:3mL 5 KES3748.00
Mixtard 30, Human Insulin Pre-filled pen/Flexipen Soluble 30%/NPH 70%, 100iu/mL:3mL 1 KES3370.00
Jusline N. NPH. inj 100IU/mL:10mL 1 KES1055.00
Humalog. inj. 100U/mL:10mL 1 KES3,082.20
Humalog. Kwikpen 100U/mL:3mL 1 KES1,620.00
Humulin 70/30. inj 70% Insulin Isophane /30% Human Insulin 100U/mL:10mL 1 KES714.80
Humulin 70/30. inj 70% Insulin Isophane /30% Human Insulin100U/mL:3mL 5 KES4181.00
Humulin N. inj Insulin isophane suspension (NPH) 100IU:10mL 1 KES714.80
Humulin R. inj Regular Insulin,100IU:10mL 1 KES714.80
Humulin R. inj Regular Insulin,100IU:10mL 5 KES4,090.00
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