For induction: 1.5-3% inspired concentration in oxygen and nitrous oxide. Anesthesia is produced within a period of 10 minutes. For maintenance: 0.5 -2.5% with nitrous oxide in oxygen or 1.5-2.5% when used alone in oxygen.
Mode of action
Brands containing this Ingredient
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Mode of Action
It may act by enhancing inhibitory ion channels hence inhibiting excitatory activity in CNS
Use cautiously in patients with: inability to secure the airway; full stomach; cardiovascular disorders such as hypotension, constrictive pericarditis, heart failure and coronary heart disease; muscular dystrophies; myasthenia gravis; myotonias; Addisonâs disease; myxoedema. Dose is adjusted downwards in case of renal or hepatic disorders, in elderly and / or debilitated patients.
Susceptibility to malignant hyperthermia
Since it is irritant to the airways, it produces coughing; laryngospasm; apnoea