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Ofloxacin
Indications
See under indications and doses.
Dose/Application
Used in Chlamydia or Chlamydophila infections including nongonococ- cal urethritis and in mycobacterial infections such as leprosy and tuberculosis [see under uses and administration of ciprofloxacin]. Ofloxacin is given orally as the base or by intravenous infusion as the hydrochloride. The usual oral or intravenous dose ranges from 200 mg daily to 400 mg twice daily depending on the severity and the nature of the infection. Oral doses of up to 400 mg may be given as a single dose, preferably in the morning. For intravenous use a 0.2% solution is infused over 30 minutes. An oral dose of 200 mg twice daily for 3 days is suitable in women with acute uncomplicated cystitis. A 6-week course of treatment with an oral dose of 300 mg twice daily should be given for chronic bacterial prostatitis. Oral doses of 400 mg daily with clofazimine and minocycline or 400 mg monthly with rifampicin and minocycline have been recommended by WHO as alternative multidrug therapy regimens for multibacillary leprosy. As an alternative regimen for single- lesion paucibacillary leprosy WHO suggests a single dose of ofloxacin 400 mg with rifampicin and minocycline. A single 400-mg dose of ofloxacin may be given orally for uncomplicated gonorrhoea.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Exocin Eye drops 3mg/ml 5 ml KES648.00
Oflomac Tabs 200mg 60 KES1,260.00
Toflox Tabs 200mg 100 KES725.00
Nestoflox tabs 200mg 100 KES370.00
Oflobid. tabs 200mg 10 KES380.00
Oflobid. inf. 100mg/100mL 1 KES540.00
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