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Chloramphenicol
Indications
Serious infections where less potentially dangerous medicines are ineffective or contraindicated e.g. typhoid and paratyphoid fever, infections due to H. influenzae.
Dose/Application
By mouth or by intravenous injection or infusion, 50mg/kg daily in 4 divided doses [ex- ceptionally, can be doubled for severe infections such as septicaemia and meningitis, providing high doses reduced as soon as clinically indicat- ed]; child, haemophilus epiglottitis and pyogenic meningitis, 50–100mg/kg daily in divided doses [high dosages decreased as soon as clinically indicated]; neonate under 2 weeks 25mg/kg daily [in 4 divided doses]; infant 2 weeks–1 year 50mg/kg daily [in 4 divided doses]. Note: Plasma concentration monitoring required in neonates and preferred in those under 4 years of age, in the elderly, and in hepatic impairment; recommended peak plasma concentration [ap- prox. 1 hour after intravenous injection or infu- sion] 15–25mg/litre; pre-dose [ ̳trough'] concen- tration should not exceed 15mg/litre.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Chlorocide. susp 125mg/5mL:100mL 1 KES82.00
Chloramphenicol Macleods Inj 1 gm 50 KES2,250.00
Mediphenicol inj 1gm 1 KES40.00
Dawaphenicol suspension susp 125mg/5mL:60mL 1 KES25.00
Dawaphenicol suspension susp 125mg/5mL:100mL 1 KES35.00
Biophenicol susp 125mg/5mL: 60mL 1 KES45.00
Biophenicol susp 125mg/5mL:100mL 1 KES65.00
Biophenicol caps 250mg 100 KES320.00
Biophenicol caps 250mg 1000 KES2.800.00
Oramnicol. caps 250mg 1000 KES2,600.00
Kloran. susp 125mg/5mL:60mL 1 KES40.00
Kloran. susp 125mg/5mL:100mL 1 KES50.00
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