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Mercaptopurine
Indications
Leukemias, a part from chronic lymphocytic leukemia, (as a component of various chemotherapeutic regimens); an adjunct for prevention of rejection in renal, cardiac, hepatic, and pancreatic transplantations; treatment of rheumatoid arthritis unresponsive to the classical medications; treatment of inflammatory bowel disease; systemic lupus erythematosus; nephrotic syndrome; management of other immunologic diseases including myasthenia gravis, pemphigoid and pemphigus; systemic dermatomyositis, glomerulonephritis, chronic active hepatitis among others.
Dose/Application
Leukemia: Orally, 2.5 mg / kg / day in single or divided doses. In case of poor response after four weeks at this dosage, an increase in dosage to 5 mg / kg / day is tried. Maintenance-Dose: Orally, 1.5 - 2.5 mg/kg/ day. Inflammatory bowel disease: Orally, 1.5 mg /kg / day, adjusted accordingly. In case of poor response after 2-3months at this dosage, an increase in dosage to 2.5 mg / kg / day is tried.Usual dose in children: Orally, 2.5 mg / kg / day in single or divided doses. Consult specialist literature for further information.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Puri-Nethol Tablets 50 mg 25 KES6147.90
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