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It appears to diminish inflammation by inhibiting cyclo-oxygenase and lipoxy- genase, hence decreasing the production of pros- taglandins, leukotrienes and hydroxyeicosatetraenoic acids [HETEs]. It also appears to act as a scavenger of oxygen-derived free radicals, produced in greater numbers in those with inflammatory bowel disease.
Breastfeeding, pregnancy, elderly patients
GI disturbances, headache, and exacerbation of colitis