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Mesna
Indications
Prevention of urotoxic effects of oxazaphosphorines such as cyclophosphamide, ifosfamide.
Dose/Application
Antineoplastic as IV bolus: Adult: 20% of the antineoplastic dose on a weight for weight basis given IV at 4-hourly intervals, beginning at the same time as the antineoplastic inj at 0 hr, 4 and 8 hr. Children: Carry out administrations more frequently and at shorter intervals. Antineoplastic as continuous infusion: 20% of the total antineoplastic dose given by IV inj, followed by 100% of the total antineoplastic dose by IV infusion over 24 hr, and then followed by up to 50% by infusion over a further 12 hr.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
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