Pre-operative pre-medication, Pre-medication before diagnostic or surgical intervention under local anaesthesia
Pre-operative pre-medication: Adults: 10-15mg 1.M according to age and general conditions. Children 0.15-0.2mg/kg 20-30min before anaesthesia, alone or in combination with anticholinergics and possibly analgesic. Pre-medication before diagnostic or surgical intervention under local anaesthesia: 2.5 -5mg 1.v 5-10 min before operation, alone or in combination with I.V. anticholinergics.
Mode of action
Brands containing this Ingredient
1mg/ml : 5mL
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Mode of Action
Known to potentiate the inhibitory effects of gamma-aminobutyric acid [GABA] in the CNS
Use cautiously in patients with myasthenia gravis, muscular dystrophy, myotonias, muscle weakness, sleep apnoea, and respiratory diseases as these conditions may worse. Dose is adjusted downwards in case of renal or hepatic disorders and in elderly patients. It produces paradoxical excitation and increased incidence of emergence delirium especially when given orally.
Hypersensitivity to benzodiazepine
Hypotension; cough; hiccup; nausea and vomiting; headache; confusion; bronchospasm; erythema; rash; pain at the injection point; arrhythmias,; cardiorespiratory arrest.