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It is in general less active than chloramphenicol though reported to be equally effective and more actively bactericidal against Haemophilus and Neisseria ssp. Some strains resistant to chloramphenicol may be susceptible to thiamphenicol.Serious infections where less potentially dangerous medicines are ineffective or contraindicated e.g. typhoid and paratyphoid fever, infections due to H. influenzae.
Adult dose: 1.5g daily in divided doses. Children: 30-100mg/kg/day.
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