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To induce ischaemia and haemostasis at the site of an operation. It may be used with general anaesthetics which are usually not compatible with adrenaline; e.g. halothane, without fear of precipitating cardiac arrhythmias.
Usually 5 IU is diluted in 30 mL of physio- logical saline [max. dose for tissue infiltration is 5 IU]. Gynaecological surgery and laparoto- mies, more dilute solutions, e.g. 5 IU in 50 or 60 mL physiological saline are used. For ENT surgery more concentrated solutions, 5 IU in 20 mL physiological saline may be used.
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