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Hypertension; congestive heart failure; raynaud‘s syndrome; benign prostatic hyperplasia.
Hypertension, 500mcg 2–3 times daily for 3–7 days, the initial dose on retiring to bed at night [to avoid collapse, see cautions]; increased to 1mg 2–3 times daily for a further 3–7 days; further increased if necessary to max. 20mg daily in divided doses. Congestive heart failure 500mcg 2–4 times daily [initial dose at bedtime], increasing to 4mg daily in divided doses; mainte- nance 4–20mg daily in divided doses [but rarely used]. Raynaud‘s syndrome [but efficacy not established, initially 500mcg twice daily [initial dose at bedtime] increased, if necessary, after 3– 7 days to usual maintenance 1–2mg twice daily.
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