TB with other anti-tuberculous drugs.
15-35mg/kg/day to a max. daily dose 3g in 3-4 divided doses. Children, 20mg/kg/day.
Mode of action
Brands containing this Ingredient
Drug Index 2.0 is here
Our new update features a more powerful search feature and easier login. Having any issues? Contact us today.
Mode of Action
Pyrazimide is converted by pyrazinamidase to the active metabolite, pyra- zinoic acid, which is thought inhibit the fatty acid synthetase I [FASI] of M. tuberculosis
Hepatic/renal function, diabetes mellitus, history of gout
Hepatic dysfunction, safety in children and pregnancy not established.
Anorexia, fever, malaise, liver tenderness, hepatomegaly, splenomegaly, skin rashes, photosensitivity, difficult in micturition, dysuria, nausea and vomiting, sederoblastic anaemia.