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prophylaxis of Mycobacteria avium complex infection in immunocompromised patients with low CD4 count
To be administered always with another tuberculostatic agent, pregnancy, impaired liver functions, undernourished patients, late pregnancy (can cause post-natal haemorrhage), immunologic reactions with intermittent therapy, discontinue immediately if signs of hepatocells are noted, porphyria
Elevated liver enzymes; jaundice; hepatitis (not common); nausea and vomiting; anemia; leucopenia; cytopenia; haemolysis (not common); hypersensitivity reactions; coneal opacities (with long term use); orange-red colouration of urine, saliva and skin; arthralgia and myalgia; flu-like syndrome.