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Chloroquine phosphate
amoeba in the liver (used mostly after the failure of metronidazole). Indications: Malarial treatment and prophylaxis where chloroquine resistant is not encountered, rheumatic arthritis, discoid erythematosus.
Prophylaxis - 500mg weekly from one week before exposure. Continue for 4 weeks after exposure. Acute attacks: Initially 4 tablets, then 2 six hours later then 2 OD x 3/7. Children: Initial dose; 10mg/kg (of Base) then 5mg/kg after 6hours then 50mg/kg OD x 3/7.
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