Bronchospasm in asthma, bronchitis, chronic bronchitis, ephysema, bronchiectasis, premature labour.
Initially 2.5 mg TID or QID. Maintenance: 5 mg TID (Max. 15 mg/day)
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Mode of Action
It stimulates Beta-agonist in the lungs to relax bronchial smooth muscle, thereby relieving bronchospasm. This action may result from increased production of cAMP and ensuing reduction in intracellular calcium concentration caused by activation of the enzyme adenylate cyclase that catalyzes the conversion ATP to cAMP. Increased cAMP concentrations, in addition to relaxing bronchial smooth muscle, inhibit release of mediators of immediate hypersensitivity from cells, especially from mast cells.