5mg, 10mg or 20mg [max dose] OD. 4hrs before but normally 1hr before sexual intercourse
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Brands containing this Ingredient
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Mode of Action
It is a phosphodiasterase type 5 [PDE5] inhibitor that works by improving blood flow to the penis. During sexual stimulation, penile nerve endings and endothelial cells release Nitric oxide. This activates the enzyme guanylate cyclase, resulting the production of cGMP – a vasodilator.
Cardiovascular disease; anatomical deformity of penis; those with predisposition of prolonged erection; hepatic or renal impairment; bleeding disorders; active peptic ulcer.
Patients on nitrates; recent stroke, hypotension or myocardial infarction
Side effects: Headache, flushing, dyspepsia, nasal congestion, dizziness, abnorma